From: Dr. Betty Martini, D.Hum., Bettym19@mindspring.com
Date: Mon, Mar 19, 2007 12:39 pm
Subject: Imminent Health Hazard Petition: Demand to ban aspartame
Dr. Joseph Thomas of the FDA recently wrote to me to the effect that if there has been something new since 2002, we can file again our request for ban on aspartame. They completely disregarded the Imminent Health Hazard petition sent to them in 2007. Here is the recent report exposing how FDA lies and violates the law: https://www.opednews.com/articles/Proof-that-the-FDA-Lies-Ab-by-Dr-Betty-Martini-Ajinomoto_Aspartame-Carcinogen_Aspartame-Causing-Birth-Defects_Aspartame-Class-Action-Suits-180122-719.html
Dr. Thomas' email to me is at the bottom of this post.
Of course, scientific peer reviewed studies have continued and almost 100% of them show problems. FDA has not even replied to the ones prior to that time. Taken from the" US Right To Know" petition to FDA here are just some of the studies:
 Soffritti M, Belpoggi F, Degli Esposti D, Lambertini L, Tibaldi E, Rigano A. First experimental demonstration of the multipotential carcinogenic effects of aspartame administered in the feed to Sprague-Dawley rats. Environ Health Perspect. 2006 Mar; 114(3):379-85. PMID: 16507461. (article)
 Soffritti M, Belpoggi F, Tibaldi E, Esposti DD, Lauriola M. Life-span exposure to low doses of aspartame beginning during prenatal life increases cancer effects in rats. Environ Health Perspect. 2007 Sep; 115(9):1293-7. PMID: 17805418. (article)
 Soffritti M et al. Aspartame administered in feed, beginning prenatally through life span, induces cancers of the liver and lung in male Swiss mice. Am J Ind Med. 2010 Dec; 53(12):1197-206. PMID: 20886530. (abstract / article)
 Schernhammer ES, Bertrand KA, Birmann BM, Sampson L, Willett WC, Feskanich D., Consumption of artificial sweetener and sugar-containing soda and risk of lymphoma and leukemia in men and women. Am J Clin Nutr. 2012 Dec; 96(6):1419-28. PMID: 23097267. (abstract / article)
 Soffritti M1, Padovani M, Tibaldi E, Falcioni L, Manservisi F, Belpoggi F., The carcinogenic effects of aspartame: The urgent need for regulatory re-evaluation. Am J Ind Med. 2014 Apr; 57(4):383-97. doi: 10.1002/ajim.22296. Epub 2014 Jan 16. (abstract / article)
 Olney JW, Farber NB, Spitznagel E, Robins LN. Increasing brain tumor rates: is there a link to aspartame? J Neuropathol Exp Neurol. 1996 Nov; 55(11):1115-23. PMID: 8939194. (abstract)
 Azad, Meghan B., et al. Nonnutritive sweeteners and cardio metabolic health: a systematic review and meta-analysis of randomized controlled trials and prospective cohort studies. CMAJ July 17, 2017 vol. 189 no. 28 doi: 10.1503/cmaj.161390 (abstract / article)
 Fowler SP. Low-calorie sweetener use and energy balance: Results from experimental studies in animals, and large-scale prospective studies in humans. Physiol Behav. 2016 Oct 1; 164(Pt. B):517-23. doi: 10.1016/j.physbeh.2016.04.047. Epub 2016 Apr 26. (abstract)
 Vyas A et al. Diet Drink Consumption And The Risk of Cardiovascular Events: A Report from The Women's Health Initiative. J Gen Intern Med. 2015 Apr; 30(4):462-8. doi: 10.1007/s11606-014-3098-0. Epub 2014 Dec 17. (abstract / article)
 Matthew P. Pase, PhD; Jayandra J. Himali, PhD; Alexa S. Beiser, PhD; Hugo J. Aparicio, MD; Claudia L. Satizabal, PhD; Ramachandran S. Vasan, MD; Sudha Seshadri, MD; Paul F. Jacques, DSc. Sugar and Artificially Sweetened Beverages and the Risks of Incident Stroke and Dementia. A Prospective Cohort Study. Stroke. 2017 April; STROKEAHA.116.016027 (abstract / article)
 Yang M et al. Alzheimer's Disease and Methanol Toxicity (Part 1): Chronic Methanol Feeding Led to Memory Impairments and Tau Hyperphosphorylation in Mice. J Alzheimer's Dis. 2014 Apr 30. (abstract)
 Yang M et al. Alzheimer's Disease and Methanol Toxicity (Part 2): Lessons from Four Rhesus Macaques (Macaca mulatta) Chronically Fed Methanol. J Alzheimer's Dis. 2014 Apr 30. (abstract)
 Camfield PR, Camfield CS, Dooley JM, Gordon K, Jollymore S, Weaver DF. Aspartame exacerbates EEG spike-wave discharge in children with generalized absence epilepsy: a double-blind controlled study. Neurology. 1992 May; 42(5):1000-3. PMID: 1579221. (abstract)
 Maher TJ, Wurtman RJ. Possible neurologic effects of aspartame, a widely used food additive. Environ Health Perspect. 1987 Nov; 75:53-7. PMID: 3319565. (abstract / article)
 Wurtman RJ. Aspartame: possible effect on seizure susceptibility. Lancet. 1985 Nov 9; 2(8463):1060. PMID: 2865529. (abstract)
 Choudhary AK, Lee YY. Neurophysiological symptoms and aspartame: What is the connection? Nutr Neurosci. 2017 Feb 15:1-11. doi: 10.1080/1028415X.2017.1288340. (abstract)
 Onaolapo AY, Onaolapo OJ, Nwoha PU. Aspartame and the hippocampus: Revealing a bi-directional, dose/time-dependent behavioural and morphological shift in mice. Neurobiol Learn Mem. 2017 Mar; 139:76-88. doi: 10.1016/j.nlm.2016.12.021. Epub 2016 Dec 31. (abstract)
 Humphries P, Pretorius E, Naud. Direct and indirect cellular effects of aspartame on the brain. Eur J Clin Nutr. 2008 Apr; 62(4):451-62. (abstract / article)
 Tsakiris S, Giannoulia-Karantana A, Simintzi I, Schulpis KH. The effect of aspartame metabolites on human erythrocyte membrane acetylcholinesterase activity. Pharmacology Res. 2006 Jan; 53(1):1-5. PMID: 16129618. (abstract)
 Park CH et al. Glutamate and aspartate impair memory retention and damage hypothalamic neurons in adult mice. Toxicology Letters. 2000 May 19; 115(2):117-25. PMID: 10802387. (abstract)
 Walton RG, Huda R, Green-Waite R. Adverse reactions to aspartame: double-blind challenge in patients from a vulnerable population. J. Biol Psychiatry. 1993 Jul 1-15; 34(1-2):13-7. PMID: 8373935. (abstract / article)
 Yokogoshi H, Roberts CH, Caballero B, Workman RJ. Effects of aspartame and glucose administration on brain and plasma levels of large neutral amino acids and brain 5-hydroxyindoles. Am J Clin Nutr. 1984 Jul; 40(1):1-7. PMID: 6204522. (abstract)
 Olney JW, Ho OL. Brain Damage in Infant Mice Following Oral Intake of Glutamate, Aspartate or Cysteine. Nature. 1970 Aug 8; 227(5258):609-11. PMID: 5464249. (abstract)
 Blumenthal HJ, Vance DA. Chewing gum headaches. Headache. 1997 Nov-Dec; 37(10):665-6. PMID: 9439090. (abstract / article)
 Van den Eeden SK, Koepsell TD, Longstreth WT Jr, van Belle G, Daling JR, McKnight B. Aspartame ingestion and headaches: a randomized crossover trial. Neurology. 1994 Oct; 44(10):1787-93. PMID: 7936222. (abstract)
 Lipton RB, Newman LC, Cohen JS, Solomon S. Aspartame as a dietary trigger of headache. Headache. 1989 Feb; 29(2):90-2. PMID: 2708042. (abstract)
 Koehler SM, Glares A. The effect of aspartame on migraine headache. Headache. 1988 Feb; 28(1):10-4. PMID: 3277925. (abstract)
 Julie Lin and Gary C. Curhan. Associations of Sugar and Artificially Sweetened Soda with Albuminuria and Kidney Function Decline in Women. Clin J Am Soc Nephrol. 2011 Jan; 6(1): 160166. (abstract / article)
 Gul SS, Hamilton AR, Munoz AR, Phupitakphol T, Liu W, Hyoju SK, Economopoulos KP, Morrison S, Hu D, Zhang W, Gharedaghi MH, Huo H, Hamarneh SR, Hodin RA. Inhibition of the gut enzyme intestinal alkaline phosphatase may explain how aspartame promotes glucose intolerance and obesity in mice. Appl Physiol Nutr Metab. 2017 Jan; 42(1):77-83. doi: 10.1139/apnm-2016-0346. Epub 2016 Nov 18. (abstract / article)
 Susan E. Swithers, Artificial sweeteners produce the counterintuitive effect of inducing metabolic derangements. Trends Endocrinol Metab. 2013 Sep; 24(9): 431441. (article)
 Guy Fagherazzi, A Vilier, D Saes Sartorelli, M Lajous, B Balkau, F Clavel-Chapelon. Consumption of artificially and sugar-sweetened beverages and incident type 2 diabetes in the Etude Epidologique aupres femmes de la Mutuelle Grale de Education Nationale European Prospective Investigation into Cancer and Nutrition cohort. Am J Clin Nutr. 2013, Jan 30; doi: 10.3945/ ajcn.112.050997 ajcn.050997. (abstract / article)
 Suez J et al. Artificial sweeteners induce glucose intolerance by altering the gut microbiota. Nature. 2014 Oct 9; 514(7521). PMID: 25231862. (abstract / article)
 Kuk JL, Brown RE. Aspartame intake is associated with greater glucose intolerance in individuals with obesity. Appl Physiology Nutr Metab. 2016 Jul; 41(7):795-8. doi: 10.1139/apnm-2015-0675. Epub 2016 May 24. (abstract)
 PalmnMSA, Cowan TE, Bomhof MR, Su J, Reimer RA, Vogel HJ, et al. (2014) Low-Dose Aspartame Consumption Differentially Affects Gut Microbiota-Host Metabolic Interactions in the Diet-Induced Obese Rat. PLoS ONE 9(10): e109841. (article)
 Halldorsson TI, Strm M, Petersen SB, Olsen SF. Intake of artificially sweetened soft drinks and risk of preterm delivery: a prospective cohort study in 59,334 Danish pregnant women. Am J Clin Nutr. 2010 Sep; 92(3):626-33. PMID: 20592133. (abstract / article)
 Meghan B. Azad, PhD; Atul K. Sharma, MSc, MD; Russell J. de Souza, RD, ScD; et al. Association Between Artificially Sweetened Beverage Consumption During Pregnancy and Infant Body Mass Index. JAMA Pediatr. 2016; 170(7):662-670. (abstract)
 Mueller NT, Jacobs DR Jr, MacLehose RF, Demerath EW, Kelly SP, Dreyfus JG, Pereira MA. Consumption of caffeinated and artificially sweetened soft drinks is associated with risk of early menarche. Am J Clin Nutr. 2015 Sep; 102(3):648-54. doi: 10.3945/ajcn.114.100958. Epub 2015 Jul 15. (abstract  Ashok I, Poornima PS, Wankhar D, Ravindran R, Sheeladevi R. Oxidative stress evoked damages on rat sperm and attenuated antioxidant status on consumption of aspartame. Int J Impot Res. 2017 Apr 27. doi: 10.1038/ijir.2017.17. (abstract / article)
 Finamor I, Pz S, Bressan CA, Brenner CE, Rius-Pz S, Brittes PC, Cheiran G, Rocha MI, da Veiga M, Sastre J, Pavanato MA., Chronic aspartame intake causes changes in the trans-sulphuration pathway, glutathione depletion and liver damage in mice. Redox Biol. 2017 Apr; 11:701-707. doi: 10.1016/j.redox.2017.01.019. Epub 2017 Feb 1. (abstract / article
 Lebda MA, Tohamy HG, El-Sayed YS. Long-term soft drink and aspartame intake induces hepatic damage via deregulation of adipocytokines and alteration of the lipid profile and antioxidant status. Nutr Res. 2017 Apr 19. pii: S0271-5317(17)30096-9. doi: 10.1016/j.nutres.2017.04.002. [Epub ahead of print] (abstract)
 Sharma A, Amarnath S, Thulasimani M, Ramaswamy S. Artificial sweeteners as a sugar substitute: Are they really safe? Indian J Pharmacol 2016; 48:237-40 (article)
Above are 41 studies the FDA has chosen to ignore and failed to answer. They keep saying "show us the science," but when you show the science to FDA they ignore it. In the case of the Ramazzini Studies, they talk about sick rats and absurd excuses. They know very well this is a lifetime study because so much cancer comes late in life. The rats in the end had respiratory disease because respiratory disease is the dying process and they were dying. When aspartame makes world news because it's so deadly, FDA again ignores it or contrives an excuse that has no validity, as in this case.
There is no way to get away from the fact aspartame causes cancer in view of the fact their own FDA lead scientist, Dr. Adrian Gross, told the Senate on 8/1/85 that aspartame is on the market illegally because it violates the Delaney Amendment, because without a shadow of a doubt, it causes brain tumors and brain cancer. So they have no excuse for aspartame being on the market illegally. Dr. Adrian Gross wrote that because aspartame causes cancer, the FDA should not have been able to set any kind of allowable daily intake whatsoever.
Along comes Harvard University which announces their study on aspartame and cancer is the strongest and the longest. http://www.mpwhi.com/harvard_sorry_they_told_you_aspartame_is_bad.htm This is the perfect example of the aspartame industry's power. As soon as this study was published and was sent all over the world, Harvard apologized for publishing the study, saying it was weak science. First, why would anyone say they used weak science and how could the strongest and the longest be the weakest? The definition for strongest is "physically powerful." How could something physically powerful be weak? Industry must have been running low on excuses that day. Who is there to call at Harvard University on who influenced them to make the apology? (Certainly not the Fatal Drugs Allowed folks who are part of the cover-up!) FDA scientists admitted in 2009 they were broken and gave examples of corruption, even admitting they feared reprisals for speaking out: http://www.mpwhi.com/fda_claims_they_are_fundamentally_broken.htm Many studies are done outside of the United States. A translator, Norma Vera, contacted me and gave an affidavit that she translated aspartame studies done in 6 countries for G. D. Searle. They used people in poor villages and used a lot of aspartame. Victims had seizures and brain tumors. She said it hardened the synovial fluids which accounts for the joint pain that so many experienced, which is also listed on the FDA report of 92 symptoms from four types of seizures to coma and death. One pregnant woman hemorrhaged and lost her baby and then disappeared. She may have died, and the truth will never be known, thanks to Searle's concealing of the evidence.
This recent study from Medscape shows dementia and Strokes: https://www.medscape.com/viewarticle/878894
Here is one from Canada study showing high blood pressure, heart disease, diabetes and obesity. https://globalnews.ca/news/3599359/artificial-sweeteners-are-tied-to-long-term-weight-gain
Another from Canada: https://www.thestar.com/life/health_wellness/nutrition/2016/05/09/drinking-diet-soda-while-pr The FDA only pays attention to industry studies, citing the ones that couldn't possibly be valid. You simply can't take a chemical poison and have it show safety. G. D. Searle had years to produce safe studies and of course couldn't do it; this is the reason the FDA tried to have them indicted for fraud!
G. D. Searle did things like excise malignant brain tumors from rats and put them back in the study. When the rats died, they resurrected them on paper. The Board of Inquiry of the FDA revoked the petition for approval, stating aspartame could not be proven safe and that it caused brain tumors. So how could industry studies now prove safety, especially when they have their own industry research front group, ILSI (International Life Sciences Institute)? As explained to me by an aspartame victim who worked in the Atlanta office of ILSI: "if you want money, you have to get the result they want - this is not an independent organization".
To give examples of how people in the aspartame industry get away with saying their product is safe, here is information from Mark Gold of the Aspartame Toxicity Center. You can take their studies one by one and show what they did. Here are examples of industry studies:
We'll start off with four people who are well known as or were employees of The NutraSweet Company. Their full names are: Harriett H. Butchko, W. Wayne Stargel, C. Phil Comer and Dale A. Mayhew. They have put together numerous public relations reviews related to aspartame.
Then we have Hertelendy Z and Mendenhall CL (2002). These two persons performed NutraSweet-funded research testing a single dose of aspartame onpatients with chronic, stable alcoholic liver disease. (American Journal of Gastroenterology, Vol. 88)
If you go through their studies led by Mark Gold, he mentions as an example that they could use a test that could not possibly see plasma methanol increases of less than 500%. He states more details on this and other deceptive practices related to aspartame and methanol are at: http://www.holisticmed.com/aspartame/abuse/methanol.htm He discusses one of many single day studies funded by NutraSweet or industry trade groups which are used in NutraSweet funded reviews to proclaim aspartame "safety."
One review by EFSA, the European Food Safety Association, was plagiarized from an aspartame manufacturer review. Here is that report: http://www.holisticmed.com/aspartame/EFSA-Draft-Plagiarism.htm EFSA was reported to Olaf, a European organization having to do with fraud. They found only one person made the decision, not a committee. The European Commission, Scientific Committee on Food was also reported. It was clear cut that no committee made a decision on aspartame, just one person. So the European Commission became inactive, and EFSA was set up hoping to avoid this loyalty to industry. When the Ramazzini Studies were done proving aspartame to be a multipotential carcinogen beyond any shadow of a doubt the aspartame industry stepped in to get EFSA not to accept them making up absurd excuses. Finally, Dr. Herman Koeter, who headed EFSA resigned saying, "We were pressured by industry to hijack science!!" The FDA, as expected, refused to accept the studies in order to protect industry. The studies were so prestigious that Dr. Soffritti received an award for his cancer/aspartame research that had been given only twice in history.
More on industry funded studies of aspartame. Let's take the sterling example of Arthur S. Leon, who conducted research funded by the aspartame manufacturer, G. D. Searle. He had 50 healthy subjects take aspartame for 24 weeks and 51 healthy subjects take a placebo for 24 weeks. There was a 50% increase in adverse reactions in the aspartame group. But what Leon did was split the reactions into 14 subcategories, so that within each tiny subcategory they could claim no "statistically significant" increase in adverse reactions. The aspartame was given in slow-dissolving capsules which tremendously slow down the absorption of the methanol, aspartic acid, and phenylalanine, so that blood levels do not change nearly as much.
They really know the ropes and how to conceal such damning scientific and medical evidence, but the public doesn't have a clue what is going on. Take two more, C. Benninger and LMJ de Sonneville. These two persons conducted research funded by the NutraSweet Company. Their study was conducted to "evaluate whether even very small imbalances of phe [phenylalanine] (derived from aspartame) in relation to LNAA [Large Neutral Amino Acids] have any effect on cognitive function and brain electrical wave activity in PKUH [PKU Heterozygotes]." Everyone agrees that aspartame ingestion in liquids leads to a spike in plasma phenylalanine levels (especially compared to other Large Neutral Amino Acids) that compete for receptors along the blood brain barrier. However, these researchers gave aspartame in slow-dissolving capsules so that the plasma phenylalanine levels had very little change. This design problem pretty much invalidated the whole goal of their study related to aspartame and phe/LNAA imbalances. But this type of ridiculous experimental design is typical for industry-funded research.
Take George U. Liepa who was part of a NutraSweet Company-funded study of diabetic patients with chronic renal failure. It was one of their many single-dose studies. The more vulnerable the subjects, the shorter the study. The whole idea of the study was to look at plasma amino acid levels: "Effect of aspartame on plasma amino acid profiles of diabetic patients with chronic renal failure." But as mentioned above, the study was invalidated by giving the aspartame in slow-dissolving capsules which has been proven by the industry's own consultants to prevent plasma amino acid spikes. (See: "Plasma Amino Acid Concentrations in Normal Adults Administered Aspartame in Capsules or Solution: Lack of Bioequivalence," Metabolism, Volume 36, No. 5, page 507-512.) All you have to know about any industry researcher related to aspartame and methanol (like K. E. McMartin and Tephly) is available at: http://www.holisticmed.com/aspartame/abuse/methanol.html
McMartin was part of aspartame and methanol research supported by the aspartame manufacturer, G.D. Searle. They used a methanol test developed in 1969 that would not show a plasma methanol increase of less than ~500%. Raif Geha conducted research funded by the NutraSweet Company related to aspartame and allergic-like reactions (specifically urticaria/angioedema). Dr. Anthony Kulczycki Jr., M.D. reviewed the study design from 1986 to 1987 and refused to take part because of the flaws in the design of the study. Pretty much all NutraSweet-funded are designed to make it nearly impossible to find adverse reactions. And if adverse reactions are found (like in the Leon study mentioned above), statistical acrobatics are performed to claim that no adverse reactions were found. You can read about Kulczycki's critique of Geha's research and his own findings related to aspartame in the Journal of Allergy and Clinical Immunology, February 1995, pg. 639-640.
Albert Koestner did two aspartame pre-approval studies in the early 1980's to assess the prospective brain cancer potential of aspartame in rats. His article was published in an aspartame industry book in 1984, "Aspartame: Physiology and Biochemistry." He relied on the stated results of the pre-approval studies conducted by the manufacturer despite testimony from U. S. Food and Drug Administration investigators who said things like: "They [G.D. Searle] lied and they didn't submit the real nature of their observations because had they done that it is more than likely that a great number of these studies would have been rejected simply for adequacy. What Searle did, they took great pains to camouflage these shortcomings of the study. As I say filter and just present to the FDA what they wished the FDA to know and they did other terrible things for instance animals would develop tumors while they were under study. Well they would remove these tumors from the animals." [FDA Toxicologist and Task Force member, Dr. Adrian Gross] "[Searle's studies were] incredibly sloppy science. What we discovered was reprehensible." [FDA Commissioner Alexander Schmidt]
These are just a few of the examples of industry funded studies and the public, very few of whom are chemists, have no idea of the maneuvering to try and get a poison to show safety.
The truly worst crime committed by FDA was the sealing of the teratology studies that showed neural tube defects, spinal bifida and cleft palate for starters. I would not even known about them had not the FDA's own Jerome Bressler when he retired pleaded with me to find these studies and add them back to his Bressler Report because people were using this poison without knowing what they could do to their babies and the horrors aspartame can cause.
It took me 8 years to find these studies and add them back to his report. Read all about it: http://www.mpwhi.com/complete_bressler_report.pdf So now we have a global epidemic of autism. Here is the chapter on autism from Dr. Woodrow Monte's book, "While Science Sleeps: A Sweetener Kills" - http://www.rense.com/general96/asparautism.html
When Dr. Ralph Walton did research that was broadcasted on 60 Minutes, he found that 92% of all studies showed problems aspartame triggers or precipitates, and said if you eliminate 6 studies the FDA had something to do (the new FDA after Arthur Hull Hayes was appointed to over-rule the Board of Inquiry no longer exposed aspartame) and one pro aspartame summary, 100% of independent studies showed the problems aspartame causes. http://sweetremedyfilm.blogspot.com/p/dr-ralph-waltons-compiled-list-of-non.html Since then again almost 100% of independent, scientific peer reviewed studies show the problems.
When US Right to Know sent in these studies, the FDA responded that " they needed more time." That was in 2015. The modus operandi of the FDA is postpone or not answer. I still have 24 questions I sent to the FDA under FOIA for answering almost three decades ago and they haven't been answered. Newt Gingrich when he was Speaker of the House had an aide work on getting the FDA to answer the questions and the FDA denied even the Speaker of the House's demand for answers. (When do people take the "Fifth"? When they are guilty!
So this Imminent Health Hazard Demand for Ban being sent to FDA is based on these undeniable facts:
(1) Aspartame has shown itself to be a chemical poison by scientific peer reviewed studies the entire time it's been on the market and before and FDA ignores the science and refuses to accept them as valid studies that should remove aspartame from the market. How can the FDA not accept hundreds of examples of independent scientific peer-reviewed research?
(2) They postpone any answers to questions because they know to answer them honestly would result in aspartame being taken off the market.
(3) When you point out to the FDA they are using propaganda they not only won't change and tell the truth but continue the lie and misinformation. As an example, they tell the public there is more methanol in oranges than in aspartame, thus getting them to believe the methanol is safe. In reality in nature methanol is always accompanied by ethanol which is the antidote to methanol toxicity, which takes it safely out of your body. There is no ethanol in aspartame. This is what they should have said. Further, in nature aspartame binds to pectin and again takes it safely out of your body. When aspartic acid and phenylalanine are brought up, they say they are the building blocks of protein. They know perfectly well there are amino acids you cannot isolate. In nature, they are in balance. Isolated aspartic acid is an excitotoxin that stimulates the neurons of the brain to death causing brain damage of varying degrees. Phenylalanine as an isolate is a neurotoxin. Then the molecule breaks down to diketopiperazine, the brain tumor agent that triggered brain tumors in original studies.
Here the propaganda is answered with references by the Aspartame Toxicity Center: http://www.holisticmed.com/aspartame/offasprt.html
(4) They are telling the public aspartame doesn't cause cancer because they know it's illegally on the market. One of the top scientists on aspartame at FDA at the time of the aspartame investigation was Dr. Adrian Gross who told the Senate that beyond a shadow of a doubt aspartame caused brain tumors and brain cancer and violated the Delaney Amendment. FDA set an allowable daily intake when Dr. Gross told the Senate they should not have been able to set an ADI because it causes cancer. So today the FDA lies to the public and denies Dr. Gross' investigation saying they addressed the idea. They have not addressed the idea as I'm the one who brought it up on the original petition and again on the imminent health hazard petition I filed in 2007. Aspartame is on the market illegally.
As more independent studies come in confirming that aspartame causes all types of cancer, the FDA ignores them and/or says they won't accept them.
(5) Aspartame is an imminent health hazard because from day one, it has precipitated or triggered enough diseases to fill a 1000 page medical text, "Aspartame Disease: An Ignored Epidemic" by the late world expert, H. J. Roberts, M.D. http://www.amazon.com and is a regular killing machine as brought out in "While Science Sleeps: A Sweetener Kills" by Dr. Woodrow Monte.
(6) Aspartame is a drug masquerading as an additive - in reality an excitoneurotoxic, genetically engineered, carcinogenic drug, adjuvant and teratogen. It damages the mitochondria and interacts with drugs and vaccines. It was even given to me and I stopped breathing three times. http://www.mpwhi.com/iatrogenesis_aspartame.htm
(7) The whole country is talking about opioids and people dying, and yet the FDA knows perfectly well that aspartame and opioids violently interact, and that's one of the main reasons why the death rate is so high. Here is a study: https://www.researchgate.net/publication/7751709_Possible_analgesic_and_anti-inflammatory_interactions_of_aspartame_with_opioids_and_NSAIDs Yet FDA refuses to take the deadly chemical poison aspartame off the market.
(8) Section 402 of FDC Act 21 provides a food is adulterated if it contains, in whole or in part "...a decomposed substance or if it is otherwise unfit for food" The NSDA, now called American Beverage, in the protest against aspartame approval in 1983 recorded this, as found in the Congressional Record of May 7, 1985, Page S 5509, Senate. NSDA knew aspartame decomposes in soft drinks. They objected: "Searle has not demonstrated to a reasonable certainty that aspartame and its degradation products are safe for use in soft drinks. Aspartame is inherently markedly and uniquely unstable in aqueous media. In a liquid such as a soft drink aspartame will degrade as a function of temperature and pH." S5507, May 7, 1985. It also violates Interstate Commerce laws because you are not allowed to ship an adulterated product for sale.
(9) Aspartame caused horrible birth defects in original studies and there is not even a pregnancy warning. The extent to which FDA covered it up is a heinous crime, even sealing them from the Bressler Report which exposed them. MIT reports that by 2025, one out of two children will be born autistic. While they think its Roundup, another poison allowed to be on the market, it is aspartame causing everything from neural tube defects to autism to many kinds of cancer.
Immediately, aspartame's FDA approval should be revoked and rescinded. This report has shown the FDA that aspartame is such a poison the only way industry can get it to show safety is by manipulation and almost 100 per cent of independent, unbiased studies show it's deadly. There are no excuses left for FDA.
Dr. Betty Martini, D.Hum.
Founder, Mission Possible World Health International
9270 River Club Parkway
Duluth, Georgia 30097
Aspartame Toxicity Center: http://www.holisticmed.com/aspartame